Precision Nutrition · Vitamin D₃ technology

D-VITIX™ D₃ — Nature's Boost.

Rapid absorption for stronger livestock.

A 25-Hydroxyvitamin D₃ (Calcifediol) feed additive that bypasses hepatic hydroxylation — delivering the active metabolite directly to where it's needed for calcium metabolism, skeletal integrity, immune resilience, and reproductive performance.

25-Hydroxyvitamin D₃ · also known as Calcifediol or 25(OH)D₃
CAS No. 19356-17-3
Active concentrations 1.25% · 0.05%
Form Microencapsulated powder
Liquid customizable
Thermal stability Stable to 90 °C
Pellet-feed compatible
Shelf life 24 months
Cool, dry, sealed

What It Is — and why it works faster.

Conventional Vitamin D₃ (cholecalciferol) requires hepatic conversion to 25-Hydroxyvitamin D₃ before it can act on calcium and phosphorus metabolism. D-VITIX™ delivers the active metabolite directly — bypassing that liver-dependent step entirely.

D-VITIX™ D₃ is 25-Hydroxyvitamin D₃ (Calcifediol). Unlike cholecalciferol, it bypasses the liver's first hydroxylation step and delivers the active metabolite directly — the supplier reports 3–5× the biological value of vitamin D₃. The result is faster physiological impact on calcium and phosphorus regulation, immune cell signaling, and reproductive performance.

Standard reference

Cholecalciferol (Vitamin D₃)

  • AbsorptionIntestine + liver-dependent activation
  • BioactivityDelayed — requires hepatic hydroxylation
  • Circulating 25(OH)D₃Low
  • Bone impactModerate
  • Immune supportLimited
  • Feed processingLess stable
D-VITIX™ D₃

25-Hydroxyvitamin D₃ (Calcifediol)

  • AbsorptionDirect intestinal — no liver step
  • BioactivityImmediate · 3–5× biological value vs. D₃ (supplier data)
  • Circulating 25(OH)D₃High — 129.51 vs 42.80 control at D43 (SPRG broiler trial)
  • Bone impactSuperior — measured bone ash & density gains
  • Immune supportEnhanced — direct immune cell signaling
  • Feed processingStable to 90 °C (microencapsulated beadlet)

Dosing Matrix — two concentrations, one chemistry.

D-VITIX™ ships in two active concentrations. 1.25% is the high-efficiency choice for low-inclusion premixes — typical for integrators optimizing formulation efficiency. 0.05% offers higher-inclusion flexibility for commercial feed mills and pre-starters.

1.25%
25-Hydroxyvitamin D₃ · Min.

D-VITIX™ D₃ 1.25

High-efficiency inclusion for low-dosage premixes. Preferred by integrators seeking formulation efficiency in vitamin/mineral premixes and concentrated feed blends.

Poultry5 g/MT feed
Swine4 g/MT feed
0.05%
25-Hydroxyvitamin D₃ · Min.

D-VITIX™ D₃ 0.05

Higher-inclusion flexibility for feed manufacturers. Easy to dose across compound feed, pre-starters, and customizable premix formulas. Suited to commercial mills and specialty feeds.

Poultry125 g/MT feed
Swine100 g/MT feed

Best results achieved under well-balanced nutrition programs with adequate calcium and phosphorus levels. KYNAD technical team provides customized dosage recommendations based on livestock species, production goals, and feed format.

Field Trial Data — broilers, layers, breeders.

Performance data from controlled trials across multiple research institutions and commercial operations. Every figure shown is from a specific study — institution and design noted on each panel.

Broiler trial · performance & bone health

Southern Poultry Research Group (USA) 1,500 Ross × Ross 708 male broilers · 43 days · Aug–Oct 2024
Design. 4 treatments × 15 replicate pens × 25 birds. Treatments: basal diet (control); D-VITIX™ 25(OH)D₃ at 69 ppb; two other commercial 25(OH)D₃ products at their label rates (product A 69 ppb, product B 34.5 ppb). All diets carried a basal level of vitamin D₃ to prevent skeletal disease. Three-phase feeding (Starter D0–14, Grower D14–28, Finisher D28–43); grower and finisher pelleted at 80 °C. Zoalene added for coccidiosis control. Tibia and plasma sampled D21 and D43.
Parameter Control D-VITIX 25(OH)D₃ 25(OH)D₃ product A 25(OH)D₃ product B
Body weight gain, D0–43 (g/bird) 2,821 2,862 2,757 2,741
FCR, D0–43 (mortality-adjusted) 1.528 1.516 1.538 1.558
Tibia ash, D43 (%) 49.73 53.13 50.73 52.53
Serum 25(OH)D₃, D43 42.80 129.51 106.95 107.57

D-VITIX tibia ash and serum 25(OH)D₃ at D43 were significantly higher than control (different superscript letters in the trial report). Weight gain and FCR differences versus control were not statistically significant.

Layer trial · production rate & shell quality

Yichun layer farm, Jiangxi (China) Hy-Line Brown laying hens · 430–465 days
Design. Control group: basal diet. Experimental group: basal diet + 62.5 μg/kg 25(OH)D₃ (D-VITIX). Outcomes measured over commercial production cycle.
Parameter Control D-VITIX 25(OH)D₃ Δ
Production Rate (%) 83.04 85.36 +2.79%
Egg Breaking Rate (%) 1.86 1.39 −25.27%
Feed to Egg Ratio 2.254 2.171 −3.68%
Egg Weight (g) 61.53 61.89 +0.59%

Breeder trial · fertility & hatchability

Qingyuan Ma breed (China) Breeder hens at 4 laying weeks · 16-week test period
Design. Control: basal diet. Experimental: basal diet + 62.5 μg/kg 25(OH)D₃ (D-VITIX).
Parameter Control D-VITIX 25(OH)D₃ Δ
Rate of genuine eggs (%) 72.93 73.83 +1.23%
Fertility rate (%) 89.47 90.48 +1.13%
Individual chicken hatching rate (%) 65.25 66.17 +1.41%

Trial outcomes shown as published. Actual outcomes vary by operation, baseline performance, feed program, and environmental conditions. Additional layer trial data is available on request.

Application by species.

D-VITIX™ D₃ is applied across poultry and swine programs. Ruminant applications are emerging — strong scientific foundation, with early adopters reporting consistent performance gains in calves and dairy.

Poultry

Established · broilers, layers, breeders
  • Improved bone strength and walking ability in broilers
  • Enhanced shell thickness and egg quality in layers
  • Improved feed efficiency and flock uniformity
  • Reduced skeletal disorders (tibial dyschondroplasia, rickets)
  • Higher fertility and hatchability in breeder lines

Swine

Established · sows, weaners, growers, finishers
  • Supports sow bone mineralization & lactation
  • Enhances piglet viability & early growth
  • Improves ADG, FCR, carcass yield in growers
  • Reduces pre-weaning mortality & improves uniformity
  • Stronger response to E. coli & Mycoplasma challenges

Ruminants

Emerging · calves, dairy, beef
  • Supports mineral metabolism in calves & dairy
  • Enhances bone density, reduces rickets risk in young ruminants
  • Improves plasma calcium under heat stress (dairy)
  • Faster weight gain & lower diarrhea in calves
  • Reduced hoof issues in intensive-finishing bulls (pilot)

Specifications.

Complete product specifications for D-VITIX™ D₃ 1.25 and D-VITIX™ D₃ 0.05. Certificate of analysis and SDS available on request.

Parameter D-VITIX™ D₃ 1.25 D-VITIX™ D₃ 0.05
Active ingredient25-Hydroxyvitamin D₃ — Min. 1.25%25-Hydroxyvitamin D₃ — Min. 0.05%
CAS No.19356-17-3 (Calcifediol)19356-17-3 (Calcifediol)
Other ingredientsMaltodextrin, plant oil, antioxidantMaltodextrin, plant oil, antioxidant
AppearanceUniform white powder, good flowabilityUniform white powder, good flowability
Particle size>95% through 1.18 mm sieve>95% through 1.18 mm sieve
Moisture contentMax. 5%Max. 5%
SolubilityDispersible in waterDispersible in water
Thermal stabilityUp to 90 °C (pellet-feed compatible)Up to 90 °C (pellet-feed compatible)
Shelf life24 months24 months
Package20 kg cartons · sealed bags
Bulk options on request
20 kg cartons · sealed bags
Bulk options on request
Hazard classificationNon-hazardous · EC No. 1272/2008Non-hazardous · EC No. 1272/2008

Quality & analytical method.

D-VITIX™ is manufactured under ISO 9001 and FAMI-QS quality systems, with GMP-compliant production. Analytical release testing uses a validated reversed-phase HPLC/UPLC method with UV detection at 265 nm — full SOP available to QA teams on request.

Quality systems Manufactured under ISO 9001 · FAMI-QSGMP-compliant production
Test method Reversed-phase HPLC/UPLCUV detection · 265 nm
Linearity r² ≥ 0.999Range 5–80 μg/mL
Accuracy 97.8–102.1%Spike recovery
Precision %RSD ≤ 2%Inter-day ≤ 3%

Storage & handling.

D-VITIX™ is sensitive to light, heat, and humidity. Store sealed in original packaging; once opened, use quickly. Standard PPE applies during handling.

Storage

  • Dry, cool, well-ventilated Avoid direct sunlight, high humidity, and excessive heat. Original sealed packaging preserves activity through full 24-month shelf life.
  • Light-sensitive Vitamin D₃ metabolites are photodegradable. Keep packaging closed when not dispensing; minimize exposure to natural and UV light sources.
  • Use quickly once opened Once seal is broken, schedule use to minimize ambient exposure. Microencapsulated beadlet protects against routine premix conditions.

Handling

  • PPE Safety goggles recommended. Handle in a well-ventilated area. Standard feed-additive handling practices apply.
  • Hazard classification Per EC No. 1272/2008 (and amendments): non-hazardous. No hazard pictograms, warning words, or precautionary advice required.
  • Environmental Non-hazardous to environment under normal use. No foreseeable environmental threat under standard handling and disposal conditions.
Request

Request the full D-VITIX™ packet.

Technical brief, specification sheets for both concentrations, certificate of analysis, analytical method SOP, and additional layer trial data, available on request.